In October 2019, the 14th ATP (Adaptation to Technical Progress) to the CLP regulation, which includes amendments to Annexes II, III and VI, has been adopted by the European Commission. One of the amendments includes the annex VI entry for titanium dioxide (CAS 13463-67-7) as a carcinogenic category 2 by inhalation route in powder form. This will apply to titanium dioxide in powder form containing 1% or more of particles with a diameter ≤ 10 μm. The classification also requires that mandatory product labelling and warnings will be required for mixtures containing titanium dioxide.
Titanium dioxide is widely used across multiple industries. For example, titanium dioxide is used for the manufacture of chemicals, plastic products, textile, leather or fur, wood and wood products, pulp, paper and paper products, rubber products, coatings and printing inks.
This amendment has been put forward to the European Parliament and the Council of Ministers who will have a couple of months to raise any objections. If there are no objections, this amendment will come into force mid-2021.

Glycidol and acrylamide - carcinogenic above certain levels but only currently controlled in the EU - have been detected in biscuit products in Hong Kong and Malaysia. Hong Kong authorities and local regulators are testing and defining safe limits to evaluate the risks before controls are put in place.

ECHA has added six new substances to the Candidate List. All have properties that are either carcinogenic, toxic to reproduction, persistent, bio-accumulative and toxic (PBT), endocrine disrupting, or are very persistent and very bioaccumulative (vPvB). The Candidate List of substances of very high concern (SVHCs)forauthorisation now lists 197 substances.
The six new substances are:
• Pyrene, Phenanthrene and Fluoranthene are PAHs restricted in Germany under the GS mark, but not currently restricted under REACH ANNEX XVII with other PAHs;
• Benzo[k]fluoranthene is a PAH restricted under both the GS mark in Germany and REACH ANNEX XVII with other PAHs;
• 2,2-bis(4'-hydroxyphenyl)-4-;methylpentane
• 1,7,7-trimethyl-3-(.phenylmethylene)bicyclo[2.2.1]heptan-2-one

A dozen repro-toxic and carcinogenic substances will be phased out from the EU market within the next four years following the publication of the European Commission's decision. Eight repro-toxic substances, seven of them phthalates, will be banned from July 2020, with applications for individual uses accepted until January 2019. Anthracene oil and high-temperature coal-tar pitch must be phased out by October 2020, and the ban on two additional compounds classified as environmental endocrine disruptors will come into force on January 2021.